diff --git a/sdk/lib/drivers/wdf/shared/irphandlers/pnp/interruptobject.cpp b/sdk/lib/drivers/wdf/shared/irphandlers/pnp/interruptobject.cpp
index 868d2cd62ed..9265cc1d794 100644
--- a/sdk/lib/drivers/wdf/shared/irphandlers/pnp/interruptobject.cpp
+++ b/sdk/lib/drivers/wdf/shared/irphandlers/pnp/interruptobject.cpp
@@ -1505,7 +1505,18 @@ Return Value:
     // synchronize against this interrupt. For KMDF this will flush DPCs and
     // for UMDF this will send a message to reflector to flush queued DPCs.
     //
+#ifdef __REACTOS__
+    /*
+     * This causes DPCs to be flushed when SystemAffinity is already disabled.
+     * To be clear this isn't the fault of KMDF, but instead it's the fault
+     * of our current PCI.sys due to how it's architected.
+     */
+#ifndef FX_IS_KERNEL_MODE
     FlushQueuedDpcs();
+#endif
+#else
+    FlushQueuedDpcs();
+#endif
 
 #if FX_IS_KERNEL_MODE
     //